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Ketamine is a medication primarily used for starting and maintaining anesthesia. It induces a trance-like state while providing pain relief, sedation, and memory loss. Other uses include for chronic pain and for sedation in intensive care. It is also being studied as a treatment for depression. Ketamine is available as an injectable, a nasal spray, or an oral solution. Side effects include high blood pressure, increased heart rate, nausea, vomiting, confusion, hallucinations, and dissociation. Serious side effects may include seizures and kidney damage. Long-term effects of ketamine use are largely unknown.
Ketamine was first synthesized in 1962 by Calvin Larrat Stevens while working for Parke-Davis.[8][9] It was approved for use in the United States in 1970 as an intravenous anesthetic agent.[10] In the 1980s and early 1990s, ketamine was increasingly used as a recreational drug because of its hallucinogenic properties;[11] however, since the mid-1990s its legal status has been changed in many countries to control its nonmedical use.[12][13][14] In 2014, the World Health Organization's Expert Committee on Drug Dependence recommended that ketamine be scheduled under the United Nations Convention on Psychotropic Substances treaty due to its "globally recognised potential for substance abuse".[15][16][17]
Ketamine is primarily used as a veterinary anesthetic agent.[18] In addition to its primary use in animals, ketamine is also used to produce anesthesia in humans.[19][20] It has been shown to be more effective than other commonly used agents such as halothane.[21] Ketamine is considered relatively safe because it does not depress breathing like most other general anesthetics do.[22][23] However, it can cause raised blood pressure,[24] which can be dangerous in some people with uncontrolled hypertension (high blood pressure).[25]
In addition to its use as an anesthetic agent, ketamine has been shown to be effective in treating chronic pain.[26][27] A 2015 systematic review found that low-dose ketamine was effective in reducing pain in patients with chronic pain disorders such as fibromyalgia,[28] complex regional pain syndrome,[29] and cancer pain.[30] A 2016 systematic review found that there was insufficient evidence to determine whether or not ketamine was effective in treating acute pain.[31]
Ketamine has also been studied as a treatment for depression.[32][33][34][35] A 2014 systematic review found that there was insufficient evidence to determine whether or not ketamine was effective in treating major depressive disorder (MDD).[36] However, a subsequent meta-analysis published in 2016 found that low-dose ketamine infusion was associated with significant antidepressant effects compared to placebo within 24 hours of administration."[37][38.
What states Ketamine legal?
It is most commonly used in veterinary medicine as an anesthetic, but it has also been used for human medical procedures such as bronchoscopies and childbirth. Ketamine is classified as a Schedule III drug in the United States, which means that it has a potential for abuse but also recognized medical uses. There are currently no federal laws regulating ketamine, so it is legal in all states. However, some states have enacted their own laws regarding ketamine use and possession. For example, Alabama requires a prescription for ketamine use, while Louisiana prohibits its use except by licensed veterinarians. The majority of ketamine abuse occurs through illegal diversion from legitimate sources. Because it is readily available and relatively cheap, ketamine is sometimes used as a “club drug” at parties or raves. When abused in this way, it can lead to dangerous side effects such as hallucinations and out-of-body experiences. If you think you or someone you know may be abusing ketamine, please seek professional help immediately.
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Can you die from Ketamine overdose?
While it is not typically fatal, ketamine overdose can lead to serious health complications, including coma and respiratory failure. Signs and symptoms of ketamine overdose include: - High blood pressure - Rapid heart rate - Agitation - Hallucinations - Delirium - Seizures
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Can Ketamine help with anxiety?
Symptoms of anxiety can include restlessness, feeling "on edge," easily fatigued, difficulty concentrating, muscle tension, and sleep disturbance.1 While there are many effective treatments for anxiety disorders, including psychotherapy and certain medications, some people do not respond well to these conventional approaches. In recent years, there has been increasing interest in the use of ketamine for treating a variety of psychiatric conditions, including anxiety disorders.2 Ketamine is a medication that is typically used as an anesthetic for surgical procedures. It is also sometimes used illicitly as a party drug due to its dissociative effects. When used at lower doses, ketamine has been shown to have antidepressant and anti-anxiety effects.3 These effects are thought to be mediated by ketamine's action on the brain's glutamate system.4 A number of small studies have examined the use of ketamine for treating GAD and SAD with promising results.5-7 In one study, patients with treatment-resistant GAD were given either a single dose of ketamine or placebo via infusion. Those who received ketamine showed significant reductions in self-reported symptoms of anxiety compared to those who received placebo.5 Similarly, another study found that a single dose of ketamine was associated with reduced symptoms of SAD compared to placebo."6 These studies suggest that ketamine may be a promising treatment option for people with treatment-resistant anxiety disorders. However, larger studies are needed to confirm these findings before ketamine can be recommended as a standard treatment for anxiety disorders
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How many days can you go without Ketamine?
However, like all medications, ketamine has potential risks and side effects. This article will discuss how long someone can go without ketamine before experiencing withdrawal symptoms. Ketamine withdrawal symptoms usually begin within a few hours to a few days after the last dose.4 The most common symptoms include: Anxiety Depression Irritability Agitation Disturbed sleep patterns Loss of appetite4,5 Symptoms typically peak within two to three days and then gradually resolve over the next week or so.4 In some cases, however, symptoms may persist for longer periods of time.4 If you are experience withdrawal symptoms after discontinuing ketamine use, it is important to seek medical help from your healthcare provider or an addiction specialist. Untreated ketamine withdrawal can lead to serious complications, such as:6,7
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What does Ketamine do when you die?
It is also known as Special K and has a street name of Kitty. When you die, ketamine can help to ease your pain and make the process more comfortable. Ketamine works by binding to opioid receptors in the brain, which are responsible for pain relief. This means that it can help to reduce pain during the dying process. In addition, ketamine can also help to reduce anxiety and agitation, making the experience more peaceful.
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How much Ketamine should I take the first time?
First and foremost, it's important to start with a low dose. How much ketamine you take the first time will depend on your weight, tolerance, and desired effects. A general guideline is to start with 0.5-1 mg/kg, but it's always best to err on the side of caution. If you have any preexisting medical conditions or are taking any medications that might interact with ketamine, be sure to speak with your doctor before using this drug. Once you've decided how much ketamine you're going to take, it's also important to choose the right method of administration. For first-time users, it's generally recommended that you take ketamine sublingually (under the tongue) or intranasally (snorting). These methods allow you to better control the dose and avoid any potential gastrointestinal problems associated with oral consumption. After taking ketamine, the effects will begin to kick in within 5-10 minutes if taken sublingually or intranasally, and within 20-30 minutes if taken orally. The effects peak after 30-60 minutes and then gradually wear off over the course of 2-3 hours. It's important to remember that everyone reacts differently to ketamine, so be sure to go slowly at first until you know how it affects you.
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Ketamine overdose
It is also known as Special K and is used as a club drug for its hallucinogenic effects. Ketamine can cause an overdose if too much of the drug is taken. Symptoms of a ketamine overdose include high blood pressure, fast heart rate, confusion, hallucinations, and death. Treatment for a ketamine overdose may involve giving the person activated charcoal to help absorb the drug and fluids through an IV to help keep them hydrated.
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Is Ketamine legal?
In the United States, it is not approved for use in humans, but it is legal to prescribe and use “off-label.” This means that while the Food and Drug Administration (FDA) has not approved ketamine for human use, doctors are legally able to prescribe it for certain medical conditions. Ketamine was first synthesized in 1962 and was originally developed as an anesthetic agent. It works by binding to and blocking receptors in the brain that are responsible for pain perception and other sensory functions. When given at appropriate doses, ketamine produces anesthesia or sedation, making it ideal for surgical procedures. Ketamine is also known to have dissociative effects, meaning it can cause patients to feel detached from their surroundings and/or themselves. These effects make ketamine popular as a “club drug” or “party drug,” but can also be dangerous when abused. In recent years, there has been growing interest in using ketamine as a treatment for various mental health disorders, such as depression, anxiety, and post-traumatic stress disorder (PTSD). While more research is needed in this area, some studies have shown promising results. For example, one study found that a single dose of intravenous (IV) ketamine was effective in reducing depressive symptoms within 24 hours in patients who had failed to respond to other treatments. Due to its potential benefits and risks, ketamine is considered a controlled substance by the Drug Enforcement Administration (DEA). This means that it has a high potential for abuse and addiction and should only be used under the supervision of a licensed health care professional.
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Can you drink alcohol with Ketamine?
However, doing so may increase the risk of certain side effects, such as dizziness and impaired coordination. Additionally, alcohol can interact with ketamine and potentially decrease its effectiveness. Therefore, if you choose to drink alcohol while taking ketamine, it's important to do so in moderation.
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